QuestionAugust 17, 2025

What vitamin must be supplemented in a patient starting methotrexate therapy? Thiamine Niacin Folic acid Vitamin K Ascorbic acid

What vitamin must be supplemented in a patient starting methotrexate therapy? Thiamine Niacin Folic acid Vitamin K Ascorbic acid
What vitamin must be supplemented in a patient starting methotrexate therapy?
Thiamine
Niacin
Folic acid
Vitamin K
Ascorbic acid

Solution
4.5(200 votes)

Answer

Folic acid Explanation 1. Identify the vitamin affected by methotrexate Methotrexate inhibits dihydrofolate reductase, affecting folic acid metabolism. 2. Determine the necessary supplementation Folic acid supplementation is required to prevent deficiency and side effects.

Explanation

1. Identify the vitamin affected by methotrexate<br /> Methotrexate inhibits dihydrofolate reductase, affecting folic acid metabolism.<br />2. Determine the necessary supplementation<br /> Folic acid supplementation is required to prevent deficiency and side effects.
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