QuestionJuly 9, 2025

Predict Question 3 What do you think will happen after you inject TSH into the three rats? The normal rat will become hyperthyroidic and develop a goiter. The thyroidectomized rat will become hyperthyroidic and develop a goiter. The injection will have no effect on the hypophysectomized rat and , therefore, it will not develop a goiter. The normal rat will become hyperthyroidic and will not develop a goiter.

Predict Question 3 What do you think will happen after you inject TSH into the three rats? The normal rat will become hyperthyroidic and develop a goiter. The thyroidectomized rat will become hyperthyroidic and develop a goiter. The injection will have no effect on the hypophysectomized rat and , therefore, it will not develop a goiter. The normal rat will become hyperthyroidic and will not develop a goiter.
Predict Question 3 What do you think will happen after you inject TSH into the three rats? The normal rat will become hyperthyroidic and develop a goiter. The thyroidectomized rat will become hyperthyroidic and develop a goiter. The injection will have no effect on the hypophysectomized rat and , therefore, it will not develop a goiter. The normal rat will become hyperthyroidic and will not develop a goiter.

Solution
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Answer

The normal rat will become hyperthyroidic and develop a goiter. Explanation 1. Understand TSH Function Thyroid-stimulating hormone (TSH) stimulates the thyroid gland to produce thyroid hormones. Excess TSH can lead to hyperthyroidism and goiter development in a normal rat. 2. Analyze Effects on Normal Rat Injecting TSH into a normal rat increases thyroid activity, potentially causing hyperthyroidism and goiter due to overstimulation. 3. Analyze Effects on Thyroidectomized Rat A thyroidectomized rat lacks a thyroid gland, so TSH has no target to stimulate, preventing hyperthyroidism or goiter development. 4. Analyze Effects on Hypophysectomized Rat A hypophysectomized rat lacks the pituitary gland, which produces TSH. Injected TSH cannot stimulate an absent thyroid, so no hyperthyroidism or goiter occurs.

Explanation

1. Understand TSH Function<br /> Thyroid-stimulating hormone (TSH) stimulates the thyroid gland to produce thyroid hormones. Excess TSH can lead to hyperthyroidism and goiter development in a normal rat.<br /><br />2. Analyze Effects on Normal Rat<br /> Injecting TSH into a normal rat increases thyroid activity, potentially causing hyperthyroidism and goiter due to overstimulation.<br /><br />3. Analyze Effects on Thyroidectomized Rat<br /> A thyroidectomized rat lacks a thyroid gland, so TSH has no target to stimulate, preventing hyperthyroidism or goiter development.<br /><br />4. Analyze Effects on Hypophysectomized Rat<br /> A hypophysectomized rat lacks the pituitary gland, which produces TSH. Injected TSH cannot stimulate an absent thyroid, so no hyperthyroidism or goiter occurs.
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