QuestionMay 23, 2025

In eukaryotic cells, list 2 mRNA modifications that increase its stability.

In eukaryotic cells, list 2 mRNA modifications that increase its stability.
In eukaryotic cells, list 2 mRNA modifications that increase its stability.

Solution
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Answer

5' cap addition and poly-A tail addition. Explanation 1. Identify mRNA Modifications Two key modifications that increase mRNA stability in eukaryotic cells are the addition of a 5' cap and a poly-A tail. 2. Explain 5' Cap Addition The 5' cap is a modified guanine nucleotide added to the 5' end of the mRNA, protecting it from degradation and assisting in ribosome binding during translation. 3. Explain Poly-A Tail Addition The poly-A tail consists of a long chain of adenine nucleotides added to the 3' end of the mRNA, enhancing stability by preventing exonuclease degradation and aiding in nuclear export.

Explanation

1. Identify mRNA Modifications<br /> Two key modifications that increase mRNA stability in eukaryotic cells are the addition of a 5' cap and a poly-A tail.<br /><br />2. Explain 5' Cap Addition<br /> The 5' cap is a modified guanine nucleotide added to the 5' end of the mRNA, protecting it from degradation and assisting in ribosome binding during translation.<br /><br />3. Explain Poly-A Tail Addition<br /> The poly-A tail consists of a long chain of adenine nucleotides added to the 3' end of the mRNA, enhancing stability by preventing exonuclease degradation and aiding in nuclear export.
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