QuestionAugust 18, 2025

Scenario: A 45-year-old male with MDD and a history of substance use disorder is seeking treatment. According to APA guidelines, which antidepressant should be avoided? Bupropion Sertraline Fluoxetine Venlafaxine

Scenario: A 45-year-old male with MDD and a history of substance use disorder is seeking treatment. According to APA guidelines, which antidepressant should be avoided? Bupropion Sertraline Fluoxetine Venlafaxine
Scenario: A 45-year-old male with MDD and a history of substance use disorder is seeking
treatment. According to APA guidelines, which antidepressant should be avoided?
Bupropion
Sertraline
Fluoxetine
Venlafaxine

Solution
4.7(232 votes)

Answer

Bupropion Explanation Bupropion is contraindicated in individuals with a history of substance use disorder due to its potential to increase the risk of seizures, especially in those who may misuse it. The other options are generally considered safer for this population.

Explanation

Bupropion is contraindicated in individuals with a history of substance use disorder due to its potential to increase the risk of seizures, especially in those who may misuse it. The other options are generally considered safer for this population.
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