QuestionAugust 17, 2025

Methimazole exerts its effect through which of the following mechanisms? Blocking iodide transporters lodide peroxidation inhibition Inhibition of thyroglobulin proteolysis Blocking T3 receptors Inhibition of peripheral conversion of T4 to T3

Methimazole exerts its effect through which of the following mechanisms? Blocking iodide transporters lodide peroxidation inhibition Inhibition of thyroglobulin proteolysis Blocking T3 receptors Inhibition of peripheral conversion of T4 to T3
Methimazole exerts its effect through which of the following mechanisms?
Blocking iodide transporters
lodide peroxidation inhibition
Inhibition of thyroglobulin proteolysis
Blocking T3 receptors
Inhibition of peripheral conversion of T4 to T3

Solution
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Answer

Iodide peroxidation inhibition Explanation 1. Identify Methimazole's Mechanism Methimazole inhibits thyroid hormone synthesis by blocking the enzyme thyroid peroxidase, which is responsible for iodide oxidation and coupling of iodotyrosines.

Explanation

1. Identify Methimazole's Mechanism<br /> Methimazole inhibits thyroid hormone synthesis by blocking the enzyme thyroid peroxidase, which is responsible for iodide oxidation and coupling of iodotyrosines.
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