QuestionAugust 19, 2025

Question 3 What are the arguments for and against participating in a clinical trial to evaluate a treatment for an inherited disease that has no treatment? square Question 4 What is the conditional probability that the child of Peter and Martha has inherited HD?

Question 3 What are the arguments for and against participating in a clinical trial to evaluate a treatment for an inherited disease that has no treatment? square Question 4 What is the conditional probability that the child of Peter and Martha has inherited HD?
Question 3 What are the arguments for and against participating in a clinical trial to
evaluate a treatment for an inherited disease that has no treatment?
square 
Question 4 What is the conditional probability that the child of Peter and Martha has
inherited HD?

Solution
4.5(307 votes)

Answer

50% Explanation 1. Define the Genetic Inheritance Huntington's Disease (HD) is an autosomal dominant disorder. If one parent has HD, there's a 50% chance of passing it to offspring. 2. Identify Parental Genotypes Assume Peter or Martha has HD (heterozygous, Hh), and the other does not (hh). 3. Calculate Conditional Probability Use Punnett square: Hh \times hh results in 50% chance for Hh (inherited HD) and 50% for hh (not inherited).

Explanation

1. Define the Genetic Inheritance<br /> Huntington's Disease (HD) is an autosomal dominant disorder. If one parent has HD, there's a 50% chance of passing it to offspring.<br /><br />2. Identify Parental Genotypes<br /> Assume Peter or Martha has HD (heterozygous, Hh), and the other does not (hh).<br /><br />3. Calculate Conditional Probability<br /> Use Punnett square: $Hh \times hh$ results in 50% chance for Hh (inherited HD) and 50% for hh (not inherited).
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