QuestionMay 27, 2025

Which probabilities are associated with a man with hemophilia A having a child with a woman who does not have the disease and who is not a carrier? Select all that apply. All of his sons will be affected. None of his sons will be affected. All of his daughters will be carriers. None of his daughters will be carriers.

Which probabilities are associated with a man with hemophilia A having a child with a woman who does not have the disease and who is not a carrier? Select all that apply. All of his sons will be affected. None of his sons will be affected. All of his daughters will be carriers. None of his daughters will be carriers.
Which probabilities are associated with a man with hemophilia A having a child with a woman who does not have the disease and who is not a carrier? Select all that apply. All of his sons will be affected. None of his sons will be affected. All of his daughters will be carriers. None of his daughters will be carriers.

Solution
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Answer

None of his sons will be affected. ### All of his daughters will be carriers. Explanation 1. Determine Genetic Inheritance Hemophilia A is an X-linked recessive disorder. A man with hemophilia has the genotype X\(^h\)Y, and a woman without the disease or carrier status has the genotype XX. 2. Analyze Sons' Genotypes Sons inherit the Y chromosome from their father and one X chromosome from their mother. Since the mother does not carry the hemophilia gene, none of the sons will be affected. 3. Analyze Daughters' Genotypes Daughters inherit one X chromosome from each parent. They will receive X\(^h\) from their father and X from their mother, making them carriers (X\(^h\)X).

Explanation

1. Determine Genetic Inheritance<br /> Hemophilia A is an X-linked recessive disorder. A man with hemophilia has the genotype X\(^h\)Y, and a woman without the disease or carrier status has the genotype XX.<br /><br />2. Analyze Sons' Genotypes<br /> Sons inherit the Y chromosome from their father and one X chromosome from their mother. Since the mother does not carry the hemophilia gene, none of the sons will be affected.<br /><br />3. Analyze Daughters' Genotypes<br /> Daughters inherit one X chromosome from each parent. They will receive X\(^h\) from their father and X from their mother, making them carriers (X\(^h\)X).
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