QuestionJune 17, 2025

An anesthesiologist has ordered 1.8(mg)/(kg) of IV midazolam for a 45.0 kg patient about to have a surgical procedure. The drug is to be delivered over 30 min. A 250. mL IV bag of normal saline in which 1.00 g of midazolam has been dissolved is available. To what infusion rate should the IV pump be set? Round your answer to the nearest (mL)/(h) square (mL)/(h)

An anesthesiologist has ordered 1.8(mg)/(kg) of IV midazolam for a 45.0 kg patient about to have a surgical procedure. The drug is to be delivered over 30 min. A 250. mL IV bag of normal saline in which 1.00 g of midazolam has been dissolved is available. To what infusion rate should the IV pump be set? Round your answer to the nearest (mL)/(h) square (mL)/(h)
An anesthesiologist has ordered 1.8(mg)/(kg) of IV midazolam for a 45.0 kg patient about to have a surgical procedure. The drug is to be delivered over 30 min. A
250. mL IV bag of normal saline in which 1.00 g of midazolam has been dissolved is available.
To what infusion rate should the IV pump be set? Round your answer to the nearest (mL)/(h)
square (mL)/(h)

Solution
4.2(291 votes)

Answer

41 \, \frac{mL}{h} Explanation 1. Calculate the total dose required Multiply the patient's weight by the ordered dose: 1.8 \frac{mg}{kg} \times 45.0 \, kg = 81 \, mg. 2. Determine concentration of midazolam in IV bag Convert grams to milligrams: 1.00 \, g = 1000 \, mg. Concentration is \frac{1000 \, mg}{250 \, mL} = 4 \, mg/mL. 3. Calculate volume needed for the dose Divide the total dose by concentration: \frac{81 \, mg}{4 \, mg/mL} = 20.25 \, mL. 4. Convert infusion time from minutes to hours 30 \, min = 0.5 \, h. 5. Calculate infusion rate Divide volume by time: \frac{20.25 \, mL}{0.5 \, h} = 40.5 \, mL/h. 6. Round to nearest whole number Round 40.5 \, mL/h to 41 \, mL/h.

Explanation

1. Calculate the total dose required<br /> Multiply the patient's weight by the ordered dose: $1.8 \frac{mg}{kg} \times 45.0 \, kg = 81 \, mg$.<br /><br />2. Determine concentration of midazolam in IV bag<br /> Convert grams to milligrams: $1.00 \, g = 1000 \, mg$. Concentration is $\frac{1000 \, mg}{250 \, mL} = 4 \, mg/mL$.<br /><br />3. Calculate volume needed for the dose<br /> Divide the total dose by concentration: $\frac{81 \, mg}{4 \, mg/mL} = 20.25 \, mL$.<br /><br />4. Convert infusion time from minutes to hours<br /> $30 \, min = 0.5 \, h$.<br /><br />5. Calculate infusion rate<br /> Divide volume by time: $\frac{20.25 \, mL}{0.5 \, h} = 40.5 \, mL/h$.<br /><br />6. Round to nearest whole number<br /> Round $40.5 \, mL/h$ to $41 \, mL/h$.
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