QuestionJune 2, 2025

Here is a prescription Calculate how much water you need to prepare the prescription. Rx Ephidrine HCl (E=.3) 1.29 Pilocarpine nitrate (E=0.22) 0.4g Water for injection qs to make isotonic Sig. Use in the eye Water for injection necessary =(1) ml.

Here is a prescription Calculate how much water you need to prepare the prescription. Rx Ephidrine HCl (E=.3) 1.29 Pilocarpine nitrate (E=0.22) 0.4g Water for injection qs to make isotonic Sig. Use in the eye Water for injection necessary =(1) ml.
Here is a prescription Calculate how much water you need to prepare the prescription. Rx Ephidrine HCl (E=.3) 1.29 Pilocarpine nitrate (E=0.22) 0.4g Water for injection qs to make isotonic Sig. Use in the eye Water for injection necessary =(1) ml.

Solution
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Answer

49.78 mL Explanation 1. Calculate Sodium Chloride Equivalent Ephidrine HCl: 1.2 \, \text{g} \times 0.3 = 0.36 \, \text{g NaCl equivalent}; Pilocarpine nitrate: 0.4 \, \text{g} \times 0.22 = 0.088 \, \text{g NaCl equivalent}. 2. Total NaCl Equivalent Total NaCl equivalent = 0.36 \, \text{g} + 0.088 \, \text{g} = 0.448 \, \text{g}. 3. Calculate Required NaCl for Isotonic Solution For isotonic solution, 0.9\% NaCl is needed. Therefore, 0.9 \, \text{g NaCl per 100 mL}. 4. Calculate Water Needed To make the solution isotonic with 0.448 \, \text{g NaCl}, we need \frac{0.448}{0.9} \times 100 \approx 49.78 \, \text{mL} of water.

Explanation

1. Calculate Sodium Chloride Equivalent<br /> Ephidrine HCl: $1.2 \, \text{g} \times 0.3 = 0.36 \, \text{g NaCl equivalent}$; Pilocarpine nitrate: $0.4 \, \text{g} \times 0.22 = 0.088 \, \text{g NaCl equivalent}$.<br /><br />2. Total NaCl Equivalent<br /> Total NaCl equivalent = $0.36 \, \text{g} + 0.088 \, \text{g} = 0.448 \, \text{g}$.<br /><br />3. Calculate Required NaCl for Isotonic Solution<br /> For isotonic solution, $0.9\%$ NaCl is needed. Therefore, $0.9 \, \text{g NaCl per 100 mL}$.<br /><br />4. Calculate Water Needed<br /> To make the solution isotonic with $0.448 \, \text{g NaCl}$, we need $\frac{0.448}{0.9} \times 100 \approx 49.78 \, \text{mL}$ of water.
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