What is the main reason behind limited bioavailability of benzylpenicillin?
The beta-lactam ring of benzy/penicillin is highly prone to acid catalyzed intermolecular hydrolysis.
The beta-lactam ring of benzy/penicillin is highly prone to alkali catalyzed intermolecular hydrolysis.
The beta-lactam ring of benzy/penicillin is highly prone to alkali catalyzed intramolecular hydrolysis.
The beta-lactam ring of benzy/penicillin is highly prone to acid catalyzed intramolecular hydrolysis.
The beta-lactam ring of benzy/penicillin is highly prone to H2O2 catalyzed intermolecular hydrolysis.